Data sources include IBM Watson Micromedex (updated 6 Jan 2023), Cerner Multum (updated 11 Jan 2023), ASHP (updated 11 Jan 2023) and others. Promethazine HCl is a racemic compound; the empirical formula is C17H20N2SHCl and its molecular weight is 320.88. Dextromethorphan hydrobromide occasionally causes slight drowsiness, dizziness, and gastrointestinal disturbances. Avoid exposure to sunlight or tanning beds. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). These could be early signs of dangerous side effects. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you. Par Pharmaceutical - NDC products NDC labeler, manufacturer of drugs and pharmaceuticals. CONCOMITANT ADMINISTRATION OF PROMETHAZINE PRODUCTS WITH OTHER RESPIRATORY DEPRESSANTS HAS AN ASSOCIATION WITH RESPIRATORY DEPRESSION, AND SOMETIMES DEATH, IN PEDIATRIC PATIENTS. Each teaspoon (5 mL) of Promethazine HCl Syrup Plain contains 6.25 mg promethazine HCl in a flavored syrup base with a pH between 4.7 and 5.2. Last updated on Feb 1, 2021. Dry ice blasting can be faster and makes less of a mess, which is ideal for indoor cleaning. This medicine may impair your thinking or reactions. Sedating drugs may cause confusion and over-sedation in the elderly; elderly patients generally should be started on low doses of promethazine hydrochloride and dextromethorphan hydrobromide oral solution and observed closely. 24/7 Online support. : 00603-1586-58, 00603-586-58, 0060358658, 00603158658, 1586-58, 158658 UPC No. CONCOMITANT ADMINISTRATION OF PROMETHAZINE PRODUCTS WITH OTHER RESPIRATORY DEPRESSANTS HAS AN ASSOCIATION WITH RESPIRATORY DEPRESSION, AND SOMETIMES DEATH, IN PEDIATRIC PATIENTS. Promethazine Hydrochloride Tablets, USP for oral administration are available as: Promethazine Hydrochloride Tablets USP, 12.5 mg are white to off-white, biconvex, round uncoated tablets, debossed with AN and bisect on one side and 745 on the other side are supplied as: Bottles of 100: NDC 53746-745-01. It is not known whether promethazine passes into breast milk or if it could harm a nursing baby. Promethazine pregnancy and breastfeeding warnings. Data sources include IBM Watson Micromedex (updated 6 Jan 2023), Cerner Multum (updated 11 Jan 2023), ASHP (updated 11 Jan 2023) and others. Animal reproduction studies have not been conducted with the drug combinationpromethazine and dextromethorphan. CAUTION SHOULD BE EXERCISED WHEN ADMINISTERING PROMETHAZINE HYDROCHLORIDE TO PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER. Avoid drinking alcohol, which can increase some of the side effects of promethazine. Select the NDC to see product information. Alcohol 7%. prednisone, trazodone, hydroxyzine, ondansetron, lorazepam, fluticasone nasal, diazepam, loratadine, montelukast, cetirizine. Promethazine is an H 1 receptor blocking agent. Sedation, somnolence, blurred vision, dizziness; confusion, disorientation, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion; lassitude, tinnitus, incoordination, fatigue, euphoria, nervousness, diplopia, insomnia, tremors, convulsive seizures, excitation, catatonic-like states, hysteria. Para comprar Fasarax o sus genricos en , le recomendamos consultar a su farmacia ms cercana. Administration of 12.5 mg to 25 mg promethazine hydrochloride by the oral route or by rectal suppository at bedtime will provide sedation in children. Bottles of promethazine codeine cough syrup produced by Hi-Tech Pharmaceuticals Inc. and Wockhardt Ltd. subsidiary Morton Grove Pharmaceuticals Inc. sell on the streets of Houston for $750 to . Product ID: 0603-1584_153678e2-0b91-4267-a9b9-e0a9913a98a3: NDC: 0603-1584: Product Type: Dextromethorphan may produce central excitement and mental confusion. Dispense in a tight, light-resistant container with a child-resistant closure as defined in the USP. Paradoxical Reactions Hyperexcitability and abnormal movements have been reported in patients following a single administration of promethazine HCl. Extrapyramidal reactions may be treated with anticholinergic antiparkinsonian agents, diphenhydramine, or barbiturates. Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status and evidence of autonomic instability (irregular pulse or blood pressure, tachycardia, diaphoresis and cardiac dysrhythmias). The diagnostic evaluation of patients with this syndrome is complicated. Consideration should be given to the discontinuation of promethazine hydrochloride and to the use of other drugs if these reactions occur. Excessively large dosages of antihistamines, including promethazine hydrochloride, in pediatric patients may cause sudden death (see OVERDOSAGE). Each tablet for oral administration contains 12.5 mg, 25 mg or 50 mg promethazine hydrochloride, USP. Par Sterile Products develops, manufactures and . Available for Android and iOS devices. Amelioration of allergic reactions to blood or plasma. Concomitant use of other agents with anticholinergic properties should be undertaken with caution. EPINEPHRINE SHOULD NOT BE USED, since its use in a patient with partial adrenergic blockage may further lower the blood pressure. We specialize in dry ice blasting, power washing, and dustless blasting. Signs and symptoms of overdosage with promethazine HCl range from mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Promethazine hydrochloride in 12.5 mg to 25 mg doses for children and 50 mg doses for adults the night before surgery relieves apprehension and produces a quiet sleep. 2) Intensive symptomatic treatment and medical monitoring. Leukopenia and agranulocytosis has been reported, usually when promethazine hydrochloride has been used in association with other known marrow-toxic agents. Dextromethorphan should be used with caution in sedated patients, in the debilitated, and in patients confined to the supine position. Promethazine is a phenothiazine derivative which differs structurally from the antipsychotic phenothiazines by the presence of a branched side chain and no ring substitution. THE USE OF PROMETHAZINE PRODUCTS SHOULD BE AVOIDED IN PEDIATRIC PATIENTS WHOSE SIGNS AND SYMPTOMS MAY SUGGEST REYE'S SYNDROME OR OTHER HEPATIC DISEASES. Distributed by: Pharmaceutical Associates, Inc., Greenville, SC 29605. Founded Date 1978. Promethazine and codeine combination is used to relieve cough, runny or stuffy nose, sneezing, or other symptoms caused by allergies or the common cold. Promethazine Description. The average effective dose of promethazine hydrochloride for the active therapy of nausea and vomiting in children or adults is 25 mg. Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate, Losartan Potassium and Hydrochlorothiazide, Oxycodone Hydrochloride and Acetaminophen, NPI Look-Up Tool (National Provider Identifier), Generics Bidco I, LLC dba Qualitest Pharmaceuticals. It should be used with caution in persons with seizure disorders or in persons who are using concomitant medications, such as narcotics or local anesthetics, which may also affect seizure threshold. Tell any doctor who treats you that you are using promethazine. When given concomitantly with promethazine hydrochloride tablets, the dose of barbiturates should be reduced by at least one-half, and the dose of narcotics should be reduced by one-quarter to one-half. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Promethazine should not be given to a child younger than 2 years old. They both contain the same dose of active ingredients promethazine hydrochloride/codeine phosphate 6.25mg-10mg/5mL syrup. In arriving at a diagnosis, it is important to identify cases where the clinical presentation includes both serious medical illness (e.g., pneumonia, systemic infection, etc.) This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can interact with promethazine and cause medical problems or increase side effects. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. The impairment may be amplified by concomitant use of other central nervous system depressants such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore, such agents should either be eliminated or given in reduced dosage in the presence of promethazine HCl (see PRECAUTIONS - Information For Patients and Drug Interactions). Promethazine hydrochloride tablets may cause marked drowsiness or impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. Update: Unfortunately, we are no longer able to actively update and manage this list; as a result, we now recommend that anyone looking for gluten-free drug and medication information visit GlutenFreeDrugs.com, which is run by a pharmacist and actively maintained. Generic name: tromethorphan hydrobromide and promethazine hydrochloride Promethazine may lead to potentially fatal respiratory depression. Do not start using a new medication without telling your doctor. Available for Android and iOS devices. Products with assigned NDCs are displayed. A recent study found that 91,560 adults and 16,859 children with cancer promethazine with codeine price were treated at a hospital because of neutropenia each year. The administration of promethazine hydrochloride in 25 mg doses will control minor transfusion reactions of an allergic nature. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Dosage form: oral solution Promethazine with Codeine Oral Solution is a federal controlled substance (C-V) because it contains codeine that can be abused or lead to dependence. Discover how to save hours each week. Brand name: Phenergan Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you. . PROMETHAZINE HYDROCHLORIDE AND DEXTROMETHORPHAN HYDROBROMIDE ORAL SOLUTION IS CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE (see WARNINGS Black Box Warning and Use In Pediatric Patients). Promethazine hydrochloride tablets may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. PAR and Hi-Tech are pharmaceutical manufacturers. Call your doctor if your symptoms do not improve, or if they get worse while using promethazine. Do not start a new medication without telling your doctor. Promethazine HCl, a phenothiazine derivative, is designated chemically as 10 H -Phenothiazine-10-ethanamine, N,N, -trimethyl-, monohydrochloride, ()- with the following structural formula: Promethazine HCl occurs as a . All Rights Reserved. The following laboratory tests may be affected in patients who are receiving therapy with promethazine hydrochloride. Drugs having anticholinergic properties should be used with caution in patients with narrow-angle glaucoma, prostatic hypertrophy, stenosing peptic ulcer, pyloroduodenal obstruction, and bladder-neck obstruction. 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